2O6L
Crystal Structure of the UDP-Glucuronic Acid Binding Domain of the Human Drug Metabolizing UDP-Glucuronosyltransferase 2B7
Summary for 2O6L
Entry DOI | 10.2210/pdb2o6l/pdb |
Descriptor | UDP-glucuronosyltransferase 2B7 (2 entities in total) |
Functional Keywords | drug metabolism, rossman, mad, enzyme, nucleotide binding, sugar, udp-glucuronosyltransferase, ugt, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Microsome membrane; Single-pass membrane protein (Potential): P16662 |
Total number of polymer chains | 2 |
Total formula weight | 38251.44 |
Authors | Miley, M.J.,Redinbo, M.R. (deposition date: 2006-12-07, release date: 2007-05-01, Last modification date: 2023-12-27) |
Primary citation | Miley, M.J.,Zielinska, A.K.,Keenan, J.E.,Bratton, S.M.,Radominska-Pandya, A.,Redinbo, M.R. Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7. J.Mol.Biol., 369:498-511, 2007 Cited by PubMed: 17442341DOI: 10.1016/j.jmb.2007.03.066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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