2O6L

Crystal Structure of the UDP-Glucuronic Acid Binding Domain of the Human Drug Metabolizing UDP-Glucuronosyltransferase 2B7

2O6L の概要

• エントリーDOI: 10.2210/pdb2o6l/pdb
• 分子名称: UDP-glucuronosyltransferase 2B7 (2 entities in total)
• 機能のキーワード: drug metabolism, rossman, mad, enzyme, nucleotide binding, sugar, udp-glucuronosyltransferase, ugt, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Microsome membrane; Single-pass membrane protein (Potential): P16662
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38251.44

構造登録者

Miley, M.J.,Redinbo, M.R. (登録日: 2006-12-07, 公開日: 2007-05-01, 最終更新日: 2023-12-27)

• 主引用文献: Miley, M.J.,Zielinska, A.K.,Keenan, J.E.,Bratton, S.M.,Radominska-Pandya, A.,Redinbo, M.R.; Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7.; J.Mol.Biol., 369:498-511, 2007; PubMed: 17442341; DOI: 10.1016/j.jmb.2007.03.066

実験手法

X-RAY DIFFRACTION (1.8 Å)