2O5Y
Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex
Summary for 2O5Y
Entry DOI | 10.2210/pdb2o5y/pdb |
Related | 2O5X 2O5Z |
Descriptor | chimeric antibody Fab 1E9-DB3, SULFATE ION, PROGESTERONE, ... (5 entities in total) |
Functional Keywords | immunoglobulin, chimeric fab, antibody engineering, evolution of ligand recognition, immune system |
Biological source | Mus musculus, Homo sapiens (house mouse, human) More |
Total number of polymer chains | 2 |
Total formula weight | 50131.81 |
Authors | Verdino, P.,Wilson, I.A. (deposition date: 2006-12-06, release date: 2007-12-18, Last modification date: 2023-12-27) |
Primary citation | Verdino, P.,Aldag, C.,Hilvert, D.,Wilson, I.A. Closely related antibody receptors exploit fundamentally different strategies for steroid recognition. Proc.Natl.Acad.Sci.Usa, 105:11725-11730, 2008 Cited by PubMed: 18689687DOI: 10.1073/pnas.0801783105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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