2O5Y

Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0003823	molecular_function	antigen binding
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005615	cellular_component	extracellular space
L	0005886	cellular_component	plasma membrane
L	0006955	biological_process	immune response
L	0016064	biological_process	immunoglobulin mediated immune response
L	0019814	cellular_component	immunoglobulin complex
L	0050853	biological_process	B cell receptor signaling pathway
L	0070062	cellular_component	extracellular exosome
L	0071735	cellular_component	IgG immunoglobulin complex
L	0072562	cellular_component	blood microparticle

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 L 215

Chain	Residue
H	GLU56
H	SER57
L	ARG211

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 L 216

Chain	Residue
L	PRO8
L	LEU9
L	SER10
L	SER156

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 201

Chain	Residue
H	TYR27
H	SER25
H	GLY26

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 239

Chain	Residue
H	ASN84
H	SER112
H	SER113
L	ARG108
L	ALA111

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 H 240

Chain	Residue
H	ARG66
H	LYS83

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 241

Chain	Residue
H	GLU72
H	THR73
H	SER74

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 H 242

Chain	Residue
H	SER7
H	GLY8

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 H 243

Chain	Residue
H	LYS221
H	LYS222

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site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 H 244

Chain	Residue
H	LYS117
H	GLY118

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 245

Chain	Residue
H	LYS13
H	SER115
H	HOH261
L	SER202

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 H 246

Chain	Residue
H	TYR27
H	TYR27
H	MET28
H	MET28
H	TYR32
H	TYR32
H	HOH255

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 247

Chain	Residue
H	SER180
L	LYS107
L	GLY157
L	GLN160

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 H 248

Chain	Residue
H	LYS43
H	ALA44
H	LYS46

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site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE STR H 249

Chain	Residue
H	ASN35
H	TRP50
H	ALA100
H	MET100
L	ASN28

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR206-HIS212

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