2O4I

Structure of TREX1 in complex with DNA

Summary for 2O4I

• Entry DOI: 10.2210/pdb2o4i/pdb
• Related: 1Y97 2O4G
• Descriptor: 5'-D(*GP*CP*TP*AP*GP*GP*CP*AP*GP*GP*AP*AP*CP*CP*CP*CP*TP*CP*CP*TP*CP*CP*CP*CP*T)-3', Three prime repair exonuclease 1 (2 entities in total)
• Functional Keywords: trex1, exonuclease, dnaq, dna complex, ww motif, protein-protein interaction, polyproline binding motif, hydrolase-dna complex, hydrolase/dna
• Biological source: Mus musculus (house mouse)
• Cellular location: Nucleus (By similarity): Q91XB0
• Total number of polymer chains: 4
• Total formula weight: 69293.58

Authors

Brucet, M.,Macias, M.J.,Fita, I.,Celada, A. (deposition date: 2006-12-04, release date: 2007-03-13, Last modification date: 2023-08-30)

• Primary citation: Brucet, M.,Querol-Audi, J.,Serra, M.,Ramirez-Espain, X.,Bertlik, K.,Ruiz, L.,Lloberas, J.,Macias, M.J.,Fita, I.,Celada, A.; Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains.; J.Biol.Chem., 282:14547-14557, 2007; PubMed: 17355961; DOI: 10.1074/jbc.M700236200

Experimental method

X-RAY DIFFRACTION (3.5 Å)