2O4G

Structure of TREX1 in complex with a nucleotide

Summary for 2O4G

Entry DOI	10.2210/pdb2o4g/pdb
Related	1Y97 2OGI
Descriptor	Three prime repair exonuclease 1, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ... (4 entities in total)
Functional Keywords	trex1, exonuclease, dnaq, dna complex, ww motif, protein-protein interaction, polyproline binding motif, hydrolase
Biological source	Mus musculus (house mouse)
Cellular location	Nucleus (By similarity): Q91XB0
Total number of polymer chains	4
Total formula weight	110175.31
Authors	Brucet, M.,Macias, M.J.,Fita, I.,Celada, A. (deposition date: 2006-12-04, release date: 2007-03-13, Last modification date: 2023-08-30)
Primary citation	Brucet, M.,Querol-Audi, J.,Serra, M.,Ramirez-Espain, X.,Bertlik, K.,Ruiz, L.,Lloberas, J.,Macias, M.J.,Fita, I.,Celada, A. Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains. J.Biol.Chem., 282:14547-14557, 2007 Cited by PubMed: 17355961 DOI: 10.1074/jbc.M700236200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation