2O45

Structure of the 23S rRNA of the large ribosomal subunit from Deinococcus Radiodurans in complex with the macrolide RU-69874

2O45 の概要

• エントリーDOI: 10.2210/pdb2o45/pdb
• 関連するPDBエントリー: 2O43 2O44
• 分子名称: 23S rRNA, (3AS,4R,7R,8S,9S,10R,11R,13R,15R,15AR)-4-ETHYL-11-METHOXY-3A,7,9,11,13,15-HEXAMETHYL-2,6,14-TRIOXO-1-[4-(4-PYRIDIN-3-YL-1H-IMIDAZOL-1-YL)BUTYL]-10-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}TETRADECAHYDRO-2H-OXACYCLOTETRADECINO[4,3-D][1,3]OXAZOL-8-YL 2,6-DIDEOXY-3-C-METHYL-3-O-METHYL-ALPHA-L-RIBO-HEXOPYRANOSIDE (2 entities in total)
• 機能のキーワード: ribosome, macrolides, tunnel, rna
• 由来する生物種: Deinococcus radiodurans
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 934377.21

構造登録者

Baram, D.,Pyetan, E.,Auerbach-Nevo, T.,Yonath, A. (登録日: 2006-12-03, 公開日: 2007-12-04, 最終更新日: 2023-08-30)

• 主引用文献: Baram, D.,Pyetan, E.,Auerbach-Nevo, T.,Yonath, A.; Chemical Parameters Influencing Fine Tuning in the Binding of Macrolide Antibiotics to the Ribosomal Tunnel; TO BE PUBLISHED,

実験手法

X-RAY DIFFRACTION (3.6 Å)