2O40
Crystal Structure of a Chemically Synthesized 203 Amino Acid 'Covalent Dimer' HIV-1 Protease Molecule
Summary for 2O40
| Entry DOI | 10.2210/pdb2o40/pdb |
| Related PRD ID | PRD_000398 |
| Descriptor | covalent dimer HIV-1 protease, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide (3 entities in total) |
| Functional Keywords | beta-turn, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Total number of polymer chains | 1 |
| Total formula weight | 22662.63 |
| Authors | Torbeev, V.Y.,Kent, S.B.H. (deposition date: 2006-12-02, release date: 2006-12-19, Last modification date: 2023-12-27) |
| Primary citation | Torbeev, V.Y.,Kent, S.B. Convergent chemical synthesis and crystal structure of a 203 amino acid "covalent dimer" HIV-1 protease enzyme molecule. Angew.Chem.Int.Ed.Engl., 46:1667-1670, 2007 Cited by PubMed: 17397076DOI: 10.1002/anie.200604087 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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