2O3S
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38
Summary for 2O3S
Entry DOI | 10.2210/pdb2o3s/pdb |
Related | 1YH3 2O3Q 2O3R 2O3T 2O3U |
Descriptor | ADP-ribosyl cyclase 1, CYCLIC ADENOSINE DIPHOSPHATE-RIBOSE (3 entities in total) |
Functional Keywords | human cd38 e226g mutant, the catalytic pocket, cadpr formation and hydrolysis, substrate binding, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type II membrane protein: P28907 |
Total number of polymer chains | 2 |
Total formula weight | 61679.22 |
Authors | Liu, Q.,Kriksunov, I.A.,Graeff, R.,Lee, H.C.,Hao, Q. (deposition date: 2006-12-01, release date: 2006-12-12, Last modification date: 2024-10-16) |
Primary citation | Liu, Q.,Kriksunov, I.A.,Graeff, R.,Lee, H.C.,Hao, Q. Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38 J.Biol.Chem., 282:5853-5861, 2007 Cited by PubMed: 17182614DOI: 10.1074/jbc.M609093200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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