2O3S
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE CXR A 301 |
| Chain | Residue |
| A | TRP125 |
| A | HOH312 |
| A | HOH330 |
| A | HOH335 |
| A | HOH396 |
| A | HOH441 |
| A | HOH450 |
| A | HOH498 |
| A | HOH537 |
| A | HOH599 |
| A | ARG127 |
| A | LYS129 |
| A | GLU146 |
| A | ASP155 |
| A | ASP156 |
| A | VAL185 |
| A | TRP189 |
| A | THR221 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE CXR B 301 |
| Chain | Residue |
| B | TRP125 |
| B | ARG127 |
| B | LYS129 |
| B | GLU146 |
| B | ASP155 |
| B | ASP156 |
| B | VAL185 |
| B | TRP189 |
| B | SER193 |
| B | THR221 |
| B | HOH377 |
| B | HOH412 |
| B | HOH425 |
| B | HOH484 |
| B | HOH571 |
| B | HOH575 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"7961800","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
