2O2R

Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH

Summary for 2O2R

Entry DOI	10.2210/pdb2o2r/pdb
Related	2O2P 2O2Q
Descriptor	Formyltetrahydrofolate dehydrogenase, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	aldehyde dehydrogenase, fdh, oxidoreductase
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	231853.57
Authors	Tsybovsky, Y.,Donato, H.,Krupenko, N.I.,Davies, C.,Krupenko, S.A. (deposition date: 2006-11-30, release date: 2007-03-06, Last modification date: 2023-08-30)
Primary citation	Tsybovsky, Y.,Donato, H.,Krupenko, N.I.,Davies, C.,Krupenko, S.A. Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases. Biochemistry, 46:2917-2929, 2007 Cited by PubMed: 17302434 DOI: 10.1021/bi0619573 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation