2O2R
Crystal structure of the C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Formyltetrahydrofolate dehydrogenase | polymer | 517 | 56621.5 | 4 | UniProt (Q5HZB2) Pfam (PF00171) UniProt (by SIFTS) (P28037) | Rattus norvegicus (Norway rat) | |
| 2 | AA, BA, CA, DA, E... (D, A, B, C) | SULFATE ION | non-polymer | 96.1 | 21 | Chemie (SO4) | |||
| 3 | FA, J, Q, Y (D, A, B, C) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) | |||
| 4 | GA, K, R, Z (D, A, B, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | HA, IA, JA, KA (A, B, C, D) | water | water | 18.0 | 785 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 397 - 902 (UniProt: Q5HZB2)
| PDB | External Database | Details |
|---|---|---|
| Met 386 | - | initiating methionine |
| Arg 387 | - | cloning artifact |
| Gly 388 | - | cloning artifact |
| Ser 389 | - | cloning artifact |
| His 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
| Thr 395 | - | cloning artifact |
| Thr 396 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 226486.2 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 5367.4 | |
| All* | Total formula weight | 231853.6 |
