2O27
Structure of a class III RTK signaling assembly
Summary for 2O27
Entry DOI | 10.2210/pdb2o27/pdb |
Related | 2O26 |
Descriptor | Kit ligand (2 entities in total) |
Functional Keywords | stem cell factor, receptor tyrosine kinase, class iii, receptor-ligand complex, growth factor, cytokine, 4-helix bundle, signaling protein |
Biological source | Mus musculus (house mouse) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein (By similarity). Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Soluble KIT ligand: Secreted (By similarity): P20826 |
Total number of polymer chains | 2 |
Total formula weight | 32889.53 |
Authors | |
Primary citation | Liu, H.,Chen, X.,Focia, P.J.,He, X. Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases. Embo J., 26:891-901, 2007 Cited by PubMed: 17255936DOI: 10.1038/sj.emboj.7601545 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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