2NWS

Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase

2NWS の概要

• エントリーDOI: 10.2210/pdb2nws/pdb
• 関連するPDBエントリー: 1FWN 2NWR 2NX1 2NX3 2NXG 2NXH 2NXI 2NXK
• 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHOENOLPYRUVATE, ARABINOSE-5-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: kdo, kdo8p, kdo8ps, pep, a5p, transferase
• 由来する生物種: Aquifex aeolicus
• 細胞内の位置: Cytoplasm (By similarity): O66496
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60371.07

構造登録者

Kona, F.,Xu, X.,Martin, P.,Kuzmic, P.,Gatti, D.L. (登録日: 2006-11-16, 公開日: 2007-04-24, 最終更新日: 2023-08-30)

• 主引用文献: Kona, F.,Xu, X.,Martin, P.,Kuzmic, P.,Gatti, D.L.; Structural and Mechanistic Changes along an Engineered Path from Metallo to Nonmetallo 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthases.; Biochemistry, 46:4532-4544, 2007; PubMed: 17381075; DOI: 10.1021/bi6024879

実験手法

X-RAY DIFFRACTION (1.8 Å)