2NVQ

RNA Polymerase II Elongation Complex in 150 mM Mg+2 with 2'dUTP

Summary for 2NVQ

• Entry DOI: 10.2210/pdb2nvq/pdb
• Related: 1R9S 1R9T 1SFO 2E2H 2E2I 2E2J 2NVS 2NVT 2NVX 2NVY 2NVZ
• Descriptor: 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', DNA-directed RNA polymerase II subunit 9, DNA-directed RNA polymerases I/II/III subunit 10, ... (16 entities in total)
• Functional Keywords: transcription, mrna, multiprotein complex, molecular machine, dna, transferase-dna-rna hybrid complex, transferase/dna-rna hybrid
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Cellular location: Nucleus: P04050 P08518 P16370 P20434 P20436 P27999 P38902; Nucleus, nucleolus : P40422 P22139; Cytoplasm : P20435
• Total number of polymer chains: 13
• Total formula weight: 486751.35

Authors

Wang, D.,Bushnell, D.A.,Westover, K.D.,Kaplan, C.D.,Kornberg, R.D. (deposition date: 2006-11-13, release date: 2006-12-12, Last modification date: 2023-10-25)

• Primary citation: Wang, D.,Bushnell, D.A.,Westover, K.D.,Kaplan, C.D.,Kornberg, R.D.; Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis; Cell(Cambridge,Mass.), 127:941-954, 2006; PubMed: 17129781; DOI: 10.1016/j.cell.2006.11.023

Experimental method

X-RAY DIFFRACTION (2.9 Å)