2NV7
Crystal Structure of Estrogen Receptor Beta Complexed with WAY-555
Summary for 2NV7
Entry DOI | 10.2210/pdb2nv7/pdb |
Descriptor | Estrogen receptor beta, Nuclear receptor coactivator 1, 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME, ... (4 entities in total) |
Functional Keywords | estrogen receptor, estrogen receptor beta, er-beta, er, estrogen, nuclear receptor, transcription factor, agonist, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, transcription |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q92731 Nucleus (By similarity): Q15788 |
Total number of polymer chains | 4 |
Total formula weight | 56683.31 |
Authors | Mewshaw, R.E.,Bowen, M.S.,Harris, H.A.,Xu, Z.B.,Manas, E.S.,Cohn, S.T.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-11-10, release date: 2007-08-21, Last modification date: 2024-04-03) |
Primary citation | Mewshaw, R.E.,Bowen, S.M.,Harris, H.A.,Xu, Z.B.,Manas, E.S.,Cohn, S.T. ERbeta ligands. Part 5: synthesis and structure-activity relationships of a series of 4'-hydroxyphenyl-aryl-carbaldehyde oxime derivatives. Bioorg.Med.Chem.Lett., 17:902-906, 2007 Cited by PubMed: 17188490DOI: 10.1016/j.bmcl.2006.11.066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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