2NUT

Crystal Structure of the human Sec23a/24a heterodimer, complexed with the SNARE protein Sec22b

Summary for 2NUT

Entry DOI	10.2210/pdb2nut/pdb
Related	1IFQ 1M2V 2NUP
Descriptor	Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ... (5 entities in total)
Functional Keywords	human copii sec23-24 complexed with sec22, protein transport
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : Q15436 O95486 Endoplasmic reticulum membrane ; Single-pass type IV membrane protein : O75396
Total number of polymer chains	3
Total formula weight	194060.82
Authors	Mancias, J.D.,Goldberg, J. (deposition date: 2006-11-09, release date: 2007-05-22, Last modification date: 2023-08-30)
Primary citation	Mancias, J.D.,Goldberg, J. The Transport Signal on Sec22 for Packaging into COPII-Coated Vesicles is a Conformational Epitope Mol.Cell, 26:403-414, 2007 Cited by PubMed: 17499046 DOI: 10.1016/j.molcel.2007.03.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation