2NTD
Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations
Summary for 2NTD
Entry DOI | 10.2210/pdb2ntd/pdb |
Related | 1JY0 |
Descriptor | Acidic fibroblast growth factor 1, FORMIC ACID (3 entities in total) |
Functional Keywords | beta-trefoil, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05230 |
Total number of polymer chains | 4 |
Total formula weight | 67261.33 |
Authors | Dubey, V.K.,Blaber, M. (deposition date: 2006-11-07, release date: 2007-07-24, Last modification date: 2023-08-30) |
Primary citation | Dubey, V.K.,Lee, J.,Somasundaram, T.,Blaber, S.,Blaber, M. Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions J.Mol.Biol., 371:256-268, 2007 Cited by PubMed: 17570396DOI: 10.1016/j.jmb.2007.05.065 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.52 Å) |
Structure validation
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