2NTD
Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Acidic fibroblast growth factor 1 | polymer | 146 | 16688.8 | 4 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (human) | Heparin-binding growth factor 1, HBGF-1, aFGF, Beta-endothelial cell growth factor, ECGF- beta |
2 | A, B, C, D | FORMIC ACID | non-polymer | 46.0 | 11 | Chemie (FMT) | |||
3 | water | water | 18.0 | 307 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 140 (UniProt: P05230)
PDB | External Database | Details |
---|---|---|
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
Val 117 | Cys 132 | engineered mutation |
Cys 134 | Pro 149 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 66755.1 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 506.3 | |
All* | Total formula weight | 67261.3 |