2NTD

Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Acidic fibroblast growth factor 1	polymer	146	16688.8	4	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	Heparin-binding growth factor 1, HBGF-1, aFGF, Beta-endothelial cell growth factor, ECGF- beta
2	E, F, G, H, I... (A, B, C, D)	FORMIC ACID	non-polymer		46.0	11	Chemie (FMT)
3	P, Q, R, S (A, B, C, D)	water	water		18.0	307	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Val 117	Cys 132	engineered mutation
Cys 134	Pro 149	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66755.1
Non-Polymers*	Number of molecules	11
	Total formula weight	506.3
All*	Total formula weight	67261.3

*Water molecules are not included.