2NQ9

High resolution crystal structure of Escherichia coli endonuclease IV (Endo IV) Y72A mutant bound to damaged DNA

Summary for 2NQ9

• Entry DOI: 10.2210/pdb2nq9/pdb
• Descriptor: 5'-D(*AP*TP*AP*TP*CP*T)-3', 5'-D(P*(3DR)P*AP*GP*AP*T)-3', 5'-D(*AP*TP*CP*TP*GP*AP*AP*GP*TP*AP*T)-3', ... (6 entities in total)
• Functional Keywords: tim-barrel, trinuclear zn active site, hydrolase-dna complex, hydrolase/dna
• Biological source: Escherichia coli
• Total number of polymer chains: 4
• Total formula weight: 38173.03

Authors

Garcin-Hosfield, E.D.,Hosfield, D.J.,Tainer, J.A. (deposition date: 2006-10-30, release date: 2007-11-13, Last modification date: 2023-08-30)

• Primary citation: Garcin, E.D.,Hosfield, D.J.,Desai, S.A.,Haas, B.J.,Bjoras, M.,Cunningham, R.P.,Tainer, J.A.; DNA apurinic-apyrimidinic site binding and excision by endonuclease IV.; Nat.Struct.Mol.Biol., 15:515-522, 2008; PubMed: 18408731; DOI: 10.1038/nsmb.1414

Experimental method

X-RAY DIFFRACTION (1.45 Å)