2NOX

Crystal structure of tryptophan 2,3-dioxygenase from Ralstonia metallidurans

2NOX の概要

• エントリーDOI: 10.2210/pdb2nox/pdb
• 分子名称: Tryptophan 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• 機能のキーワード: helical bundle, heme protein, oxidoreductase
• 由来する生物種: Cupriavidus metallidurans
• タンパク質・核酸の鎖数: 16
• 化学式量合計: 530548.32

構造登録者

Zhang, Y.,Kang, S.A.,Mukherjee, T.,Bale, S.,Crane, B.R.,Begley, T.P.,Ealick, S.E. (登録日: 2006-10-26, 公開日: 2006-12-19, 最終更新日: 2023-08-30)

• 主引用文献: Zhang, Y.,Kang, S.A.,Mukherjee, T.,Bale, S.,Crane, B.R.,Begley, T.P.,Ealick, S.E.; Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis.; Biochemistry, 46:145-155, 2007; PubMed: 17198384; DOI: 10.1021/bi0620095

実験手法

X-RAY DIFFRACTION (2.4 Å)