2NDJ

Structural Basis for KCNE3 and Estrogen Modulation of the KCNQ1 Channel

2NDJ の概要

• エントリーDOI: 10.2210/pdb2ndj/pdb
• NMR情報: BMRB: 16621
• 分子名称: Potassium voltage-gated channel subfamily E member 3 (1 entity in total)
• 機能のキーワード: estrogen, membrane protein, ion channel
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Single-pass type I membrane protein : Q9Y6H6
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12799.58

構造登録者

Sanders, C.R.,Van Horn, W.D.,Kroncke, B.M.,Sisco, N.J.,Meiler, J.,Vanoye, C.G.,Song, Y.,Nannemann, D.P.,Welch, R.C.,Kang, C.,Smith, J.,George, A.L. (登録日: 2016-06-09, 公開日: 2016-09-21, 最終更新日: 2024-05-15)

• 主引用文献: Kroncke, B.M.,Van Horn, W.D.,Smith, J.,Kang, C.,Welch, R.C.,Song, Y.,Nannemann, D.P.,Taylor, K.C.,Sisco, N.J.,George, A.L.,Meiler, J.,Vanoye, C.G.,Sanders, C.R.; Structural basis for KCNE3 modulation of potassium recycling in epithelia.; Sci Adv, 2:e1501228-e1501228, 2016; PubMed: 27626070; DOI: 10.1126/sciadv.1501228

実験手法

SOLUTION NMR