2NA7
Transmembrane domain of human Fas/CD95 death receptor
Summary for 2NA7
Entry DOI | 10.2210/pdb2na7/pdb |
Related | 2NA6 |
NMR Information | BMRB: 25930 |
Descriptor | Tumor necrosis factor receptor superfamily member 6 (1 entity in total) |
Functional Keywords | transmembrane helix trimer, transmembrane domain, proline-containing motif, apoptosis, structural genomics, psi-biology, membrane protein structures by solution nmr, mpsbynmr |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Secreted. Isoform 6: Secreted: P25445 |
Total number of polymer chains | 3 |
Total formula weight | 9918.18 |
Authors | Fu, Q.,Chou, J.J.,Membrane Protein Structures by Solution NMR (MPSbyNMR) (deposition date: 2015-12-21, release date: 2016-01-27, Last modification date: 2024-05-15) |
Primary citation | Fu, Q.,Fu, T.M.,Cruz, A.C.,Sengupta, P.,Thomas, S.K.,Wang, S.,Siegel, R.M.,Wu, H.,Chou, J.J. Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor. Mol.Cell, 61:602-613, 2016 Cited by PubMed: 26853147DOI: 10.1016/j.molcel.2016.01.009 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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