2N8R
Productive complex between MMP-12 and synthetic triple-helical collagen, revealed through paramagnetic NMR
Summary for 2N8R
Entry DOI | 10.2210/pdb2n8r/pdb |
Related | 2poj |
NMR Information | BMRB: 25859 |
Descriptor | Macrophage metalloelastase, Collagen triple helix repeat family protein, ZINC ION, ... (5 entities in total) |
Functional Keywords | collagenolysis, matrix petalloproteinase, hydrolase-structural protein complex, hydrolase/structural protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix : P39900 |
Total number of polymer chains | 4 |
Total formula weight | 28360.81 |
Authors | Prior, S.H.,Van Doren, S.R. (deposition date: 2015-10-24, release date: 2016-02-24, Last modification date: 2016-04-27) |
Primary citation | Prior, S.H.,Byrne, T.S.,Tokmina-Roszyk, D.,Fields, G.B.,Van Doren, S.R. Path to Collagenolysis: COLLAGEN V TRIPLE-HELIX MODEL BOUND PRODUCTIVELY AND IN ENCOUNTERS BY MATRIX METALLOPROTEINASE-12. J.Biol.Chem., 291:7888-7901, 2016 Cited by PubMed: 26887942DOI: 10.1074/jbc.M115.703124 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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