2N54
Solution structure of a disulfide stabilized XCL1 dimer
Summary for 2N54
Entry DOI | 10.2210/pdb2n54/pdb |
NMR Information | BMRB: 25693 |
Descriptor | Lymphotactin (1 entity in total) |
Functional Keywords | xcl1, dimer, chemokine, metamorphic, gag-binding, hiv-1 inhibition, lymphotactin, atac, cytokine |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P47992 |
Total number of polymer chains | 2 |
Total formula weight | 20701.84 |
Authors | Tyler, R.C.,Tuinstra, R.L.,Peterson, F.F.,Volkman, B.F. (deposition date: 2015-07-07, release date: 2015-10-07, Last modification date: 2023-06-14) |
Primary citation | Fox, J.C.,Tyler, R.C.,Guzzo, C.,Tuinstra, R.L.,Peterson, F.C.,Lusso, P.,Volkman, B.F. Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation. Acs Chem.Biol., 10:2580-2588, 2015 Cited by PubMed: 26302421DOI: 10.1021/acschembio.5b00542 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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