2N08

NMR structure of a short hydrophobic 11mer peptide in 25 mM SDS solution

Summary for 2N08

• Entry DOI: 10.2210/pdb2n08/pdb
• Related: 2N09 2N0I 2N0N
• NMR Information: BMRB: 25517
• Descriptor: Short hydrophobic peptide with cyclic constraints (1 entity in total)
• Functional Keywords: hydrophobic peptide, glp-1r agonist, de novo protein
• Total number of polymer chains: 1
• Total formula weight: 1257.31

Authors

Hoang, H.N.,Song, K.,Hill, T.A.,Derksen, D.R.,Edmonds, D.J.,Kok, W.M.,Limberakis, C.,Liras, S.,Loria, P.M.,Mascitti, V.,Mathiowetz, A.M.,Mitchell, J.M.,Piotrowski, D.W.,Price, D.A.,Stanton, R.V.,Suen, J.Y.,Withka, J.M.,Griffith, D.A.,Fairlie, D.P. (deposition date: 2015-03-04, release date: 2015-04-15, Last modification date: 2015-05-27)

• Primary citation: Hoang, H.N.,Song, K.,Hill, T.A.,Derksen, D.R.,Edmonds, D.J.,Kok, W.M.,Limberakis, C.,Liras, S.,Loria, P.M.,Mascitti, V.,Mathiowetz, A.M.,Mitchell, J.M.,Piotrowski, D.W.,Price, D.A.,Stanton, R.V.,Suen, J.Y.,Withka, J.M.,Griffith, D.A.,Fairlie, D.P.; Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists.; J.Med.Chem., 58:4080-4085, 2015; PubMed: 25839426; DOI: 10.1021/acs.jmedchem.5b00166

Experimental method

SOLUTION NMR