2MTN
Solution structure of MLL-IBD complex
Summary for 2MTN
Entry DOI | 10.2210/pdb2mtn/pdb |
NMR Information | BMRB: 25171 |
Descriptor | Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein fusion (1 entity in total) |
Functional Keywords | protein-protein complex, transferase-protein binding complex, transferase/protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : O75475 |
Total number of polymer chains | 1 |
Total formula weight | 18208.90 |
Authors | Cierpicki, T.,Pollock, J.,Murai, M. (deposition date: 2014-08-23, release date: 2014-12-03, Last modification date: 2024-05-01) |
Primary citation | Murai, M.J.,Pollock, J.,He, S.,Miao, H.,Purohit, T.,Yokom, A.,Hess, J.L.,Muntean, A.G.,Grembecka, J.,Cierpicki, T. The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV. Blood, 124:3730-3737, 2014 Cited by PubMed: 25305204DOI: 10.1182/blood-2014-01-550079 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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