2MT6

Solution structure of the human ubiquitin conjugating enzyme Ube2w

Summary for 2MT6

• Entry DOI: 10.2210/pdb2mt6/pdb
• NMR Information: BMRB: 25150
• Descriptor: Ubiquitin-conjugating enzyme E2 W (1 entity in total)
• Functional Keywords: ubiquitin, ube2w, e2, ubiquitin conjugating enzyme, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q96B02
• Total number of polymer chains: 1
• Total formula weight: 17350.85

Authors

Vittal, V.,Shi, L.,Wenzel, D.M.,Brzovic, P.S.,Klevit, R.E. (deposition date: 2014-08-14, release date: 2014-11-26, Last modification date: 2015-01-14)

• Primary citation: Vittal, V.,Shi, L.,Wenzel, D.M.,Scaglione, K.M.,Duncan, E.D.,Basrur, V.,Elenitoba-Johnson, K.S.,Baker, D.,Paulson, H.L.,Brzovic, P.S.,Klevit, R.E.; Intrinsic disorder drives N-terminal ubiquitination by Ube2w.; Nat.Chem.Biol., 11:83-89, 2015; PubMed: 25436519; DOI: 10.1038/nchembio.1700

Experimental method

SOLUTION NMR