2MLP
MICROCIN LEADER PEPTIDE FROM E. COLI, NMR, 25 STRUCTURES
Summary for 2MLP
| Entry DOI | 10.2210/pdb2mlp/pdb |
| Descriptor | MCBA PROPEPTIDE (1 entity in total) |
| Functional Keywords | leader peptide, propeptide, antibiotic |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 2776.26 |
| Authors | Kim, S.,Sinha Roy, R.,Walsh, C.T.,Baleja, J.D. (deposition date: 1998-01-21, release date: 1998-07-22, Last modification date: 2024-10-23) |
| Primary citation | Roy, R.S.,Kim, S.,Baleja, J.D.,Walsh, C.T. Role of the microcin B17 propeptide in substrate recognition: solution structure and mutational analysis of McbA1-26. Chem.Biol., 5:217-228, 1998 Cited by PubMed Abstract: The peptide antibiotic microcin B17 (MccB17) contains oxazole and thiazole heterocycles formed by the post-translational modification of four cysteine and four serine residues. An amino-terminal propeptide targets the 69 amino acid precursor of MccB17 (preproMccB17) to the heterocyclization enzyme MccB17 synthetase. The mode of synthetase recognition has been unclear, because there has been limited structural information available on the MccB17 propeptide to date. PubMed: 9545435DOI: 10.1016/S1074-5521(98)90635-4 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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