2MKB
Structure of NS2(113-137) GBVB protein
Summary for 2MKB
| Entry DOI | 10.2210/pdb2mkb/pdb |
| Related | 2lzp 2lzq |
| NMR Information | BMRB: 19765 |
| Descriptor | Protease NS2-3 (1 entity in total) |
| Functional Keywords | ns2, gbvb, virus, protease, viral protein |
| Biological source | Hepatitis GB virus B (GBV-B) |
| Cellular location | Core protein: Virion (Potential). Envelope glycoprotein E1: Virion membrane; Single-pass type I membrane protein (Potential). Envelope glycoprotein E2: Virion membrane; Single-pass type I membrane protein (Potential). p13: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Protease NS2-3: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 5A: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). RNA-directed RNA polymerase: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential): Q69422 |
| Total number of polymer chains | 1 |
| Total formula weight | 3116.61 |
| Authors | Montserret, R.,Martin, A.,Penin, F. (deposition date: 2014-02-04, release date: 2014-05-07, Last modification date: 2023-06-14) |
| Primary citation | Boukadida, C.,Marnata, C.,Montserret, R.,Cohen, L.,Blumen, B.,Gouttenoire, J.,Moradpour, D.,Penin, F.,Martin, A. NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies. J.Virol., 88:7426-7444, 2014 Cited by PubMed: 24741107DOI: 10.1128/JVI.00656-14 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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