2MIP
CRYSTAL STRUCTURE OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) TYPE 2 PROTEASE IN COMPLEX WITH A REDUCED AMIDE INHIBITOR AND COMPARISON WITH HIV-1 PROTEASE STRUCTURES
Summary for 2MIP
Entry DOI | 10.2210/pdb2mip/pdb |
Descriptor | HIV-2 PROTEASE, INHIBITOR BI-LA-398 (3 entities in total) |
Functional Keywords | acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 2 |
Total number of polymer chains | 8 |
Total formula weight | 45973.07 |
Authors | Tong, L.,Pav, S.,Pargellis, C.,Do, F.,Lamarre, D.,Anderson, P.C. (deposition date: 1993-06-03, release date: 1993-10-31, Last modification date: 2019-08-14) |
Primary citation | Tong, L.,Pav, S.,Pargellis, C.,Do, F.,Lamarre, D.,Anderson, P.C. Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures. Proc.Natl.Acad.Sci.USA, 90:8387-8391, 1993 Cited by PubMed: 8378311DOI: 10.1073/pnas.90.18.8387 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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