2MIP

CRYSTAL STRUCTURE OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) TYPE 2 PROTEASE IN COMPLEX WITH A REDUCED AMIDE INHIBITOR AND COMPARISON WITH HIV-1 PROTEASE STRUCTURES

2MIP の概要

• エントリーDOI: 10.2210/pdb2mip/pdb
• 分子名称: HIV-2 PROTEASE, INHIBITOR BI-LA-398 (3 entities in total)
• 機能のキーワード: acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Human immunodeficiency virus 2
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 45973.07

構造登録者

Tong, L.,Pav, S.,Pargellis, C.,Do, F.,Lamarre, D.,Anderson, P.C. (登録日: 1993-06-03, 公開日: 1993-10-31, 最終更新日: 2019-08-14)

• 主引用文献: Tong, L.,Pav, S.,Pargellis, C.,Do, F.,Lamarre, D.,Anderson, P.C.; Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures.; Proc.Natl.Acad.Sci.USA, 90:8387-8391, 1993; PubMed: 8378311; DOI: 10.1073/pnas.90.18.8387

実験手法

X-RAY DIFFRACTION (2.2 Å)