2MH6

Solution structure of DNA duplex containing N3T-ethylene-N1I interstrand cross-link

Summary for 2MH6

• Entry DOI: 10.2210/pdb2mh6/pdb
• NMR Information: BMRB: 19620
• Descriptor: 5'-D(*CP*AP*GP*TP*TP*CP*CP*A)-3', 5'-D(*TP*GP*GP*AP*IP*CP*TP*G)-3' (2 entities in total)
• Functional Keywords: dna duplex, interstrand cross-link, dna
• Total number of polymer chains: 2
• Total formula weight: 5008.17

Authors

Denisov, A.Y.,O'Flaherty, D.K.,Noronha, A.M.,Wilds, C.J. (deposition date: 2013-11-18, release date: 2014-07-02, Last modification date: 2023-06-14)

• Primary citation: O'Flaherty, D.K.,Denisov, A.Y.,Noronha, A.M.,Wilds, C.J.; NMR Structure of an Ethylene Interstrand Cross-Linked DNA which Mimics the Lesion Formed by 1,3-Bis(2-chloroethyl)-1-nitrosourea.; Chemmedchem, 9:2099-2103, 2014; PubMed: 24931822; DOI: 10.1002/cmdc.201402121

Experimental method

SOLUTION NMR