2MH0

Solution NMR structure of the p300 Taz2:ETAD1 complex

Summary for 2MH0

• Entry DOI: 10.2210/pdb2mh0/pdb
• NMR Information: BMRB: 19610
• Descriptor: Transcription factor E2-alpha, Histone acetyltransferase p300 (2 entities in total)
• Functional Keywords: transcription-transferase complex, transcription/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P15923; Cytoplasm: Q09472
• Total number of polymer chains: 2
• Total formula weight: 14375.84

Authors

Langelaan, D.N.,Smith, S.P.,Chitayat, S. (deposition date: 2013-11-12, release date: 2014-11-12, Last modification date: 2022-08-24)

• Primary citation: Lochhead, M.R.,Brown, A.D.,Kirlin, A.C.,Chitayat, S.,Munro, K.,Findlay, J.E.,Baillie, G.S.,LeBrun, D.P.,Langelaan, D.N.,Smith, S.P.; Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A.; J.Biol.Chem., 295:4303-4315, 2020; PubMed: 32098872; DOI: 10.1074/jbc.RA119.011078

Experimental method

SOLUTION NMR