2MC2
X-ray crystallography-solution NMR hybrid structure of mouse RyR2 domain A
Summary for 2MC2
Entry DOI | 10.2210/pdb2mc2/pdb |
Related | 3IM5 3QR5 4KEI 4KEJ 4KEK |
NMR Information | BMRB: 19425 |
Descriptor | Ryanodine receptor 2 (1 entity in total) |
Functional Keywords | ryanodine receptor, type ii, alpha2 helix, metal transport |
Biological source | Mus musculus (mouse) |
Cellular location | Sarcoplasmic reticulum membrane; Multi-pass membrane protein (Probable): E9Q401 |
Total number of polymer chains | 1 |
Total formula weight | 24169.16 |
Authors | Amador, F.,Stathopulos, P.,Seabrook, G.,Ikura, M. (deposition date: 2013-08-13, release date: 2013-09-11, Last modification date: 2023-06-14) |
Primary citation | Amador, F.J.,Kimlicka, L.,Stathopulos, P.B.,Gasmi-Seabrook, G.M.,Maclennan, D.H.,Van Petegem, F.,Ikura, M. Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy. J.Mol.Biol., 425:4034-4046, 2013 Cited by PubMed: 23978697DOI: 10.1016/j.jmb.2013.08.015 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report