2M5D

Solution Structure of the Bacillus cereus Metallo-Beta-Lactamase BcII in Complex with R-Thiomandelic Acid

Summary for 2M5D

• Entry DOI: 10.2210/pdb2m5d/pdb
• Related: 2M5C
• NMR Information: BMRB: 19048
• Descriptor: Beta-lactamase 2, ZINC ION, (2R)-phenyl(sulfanyl)ethanoic acid (3 entities in total)
• Functional Keywords: bcii, metallo-beta-lactamase, r-thiomandelic acid, mercaptocarboxylate inhibitor, broad spectrum inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bacillus cereus
• Total number of polymer chains: 1
• Total formula weight: 25294.56

Authors

Karsisiotis, A.I.,Damblon, C.F.,Roberts, G.C.K. (deposition date: 2013-02-20, release date: 2013-10-09, Last modification date: 2024-05-15)

• Primary citation: Karsisiotis, A.I.,Damblon, C.F.,Roberts, G.C.; Solution structures of the Bacillus cereus metallo-beta-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid.; Biochem.J., 456:397-407, 2013; PubMed: 24059435; DOI: 10.1042/BJ20131003

Experimental method

SOLUTION NMR