2LT0

NMR structure of duplex DNA containing the beta-OH-PdG dA base pair: A mutagenic intermediate of acrolein

Summary for 2LT0

• Entry DOI: 10.2210/pdb2lt0/pdb
• Related: 2LSZ
• NMR Information: BMRB: 18454
• Descriptor: DNA (5'-D(*CP*GP*TP*AP*CP*(63G)P*CP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*AP*GP*TP*AP*CP*G)-3') (2 entities in total)
• Functional Keywords: acrolein adducts, dna lesions, damaged dna structure, dna
• Total number of polymer chains: 2
• Total formula weight: 6788.48

Authors

Zaliznyak, T.,de los Santos, C.,Lukin, M.,El-khateeb, M.,Bonala, R.,Johnson, F. (deposition date: 2012-05-09, release date: 2012-06-13)

• Primary citation: Zaliznyak, T.,Lukin, M.,El-khateeb, M.,Bonala, R.,Johnson, F.,de los Santos, C.; NMR structure of duplex DNA containing the alpha-OH-PdG.dA base pair: a mutagenic intermediate of acrolein.; Biopolymers, 93:391-401, 2010; PubMed: 20049919; DOI: 10.1002/bip.21366

Experimental method

SOLUTION NMR