2LQB
Metal binding repeat 2 of the Wilson disease protein (ATP7B)
Summary for 2LQB
| Entry DOI | 10.2210/pdb2lqb/pdb |
| NMR Information | BMRB: 18301 |
| Descriptor | Copper-transporting ATPase 2 (1 entity in total) |
| Functional Keywords | copper binding, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein (By similarity). Isoform 2: Cytoplasm. WND/140 kDa: Mitochondrion: P35670 |
| Total number of polymer chains | 1 |
| Total formula weight | 8427.71 |
| Authors | Nokhrin, S.,Dolgova, N.V.,Yu, C.,Dmitriev, O.Y. (deposition date: 2012-02-28, release date: 2013-07-03, Last modification date: 2023-06-14) |
| Primary citation | Dolgova, N.V.,Nokhrin, S.,Yu, C.H.,George, G.N.,Dmitriev, O.Y. Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification. Biochem.J., 454:147-156, 2013 Cited by PubMed: 23751120DOI: 10.1042/BJ20121656 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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