2LG2

Structure of the duplex containing HNE derived (6S,8R,11S) N2-dG cyclic hemiacetal when placed opposite dT

Summary for 2LG2

• Entry DOI: 10.2210/pdb2lg2/pdb
• Related: 2LG3
• NMR Information: BMRB: 17790
• Descriptor: DNA (5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*TP*TP*GP*CP*TP*AP*GP*C)-3'), (2R,5S)-5-pentyltetrahydrofuran-2-ol (3 entities in total)
• Functional Keywords: trans-4-hydroxynonenal, n2-dg cyclic hemiacetal, dna
• Total number of polymer chains: 2
• Total formula weight: 7500.03

Authors

Huang, H.,Wang, H.,Kozekova, A.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P. (deposition date: 2011-07-19, release date: 2012-08-01, Last modification date: 2023-06-14)

• Primary citation: Huang, H.,Wang, H.,Kozekova, A.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P.; Ring-chain tautomerization of trans-4-hydroxynonenal derived (6S,8R,11S) gamma-hydroxy-1,N2-propano-deoxyguanosine adduct when placed opposite 2'-deoxythymidine in duplex; To be Published,

Experimental method

SOLUTION NMR