2LFO

NMR structure of cl-BABP/SS complexed with glycochenodeoxycholic and glycocholic acids

Summary for 2LFO

• Entry DOI: 10.2210/pdb2lfo/pdb
• Related: 2JN3
• NMR Information: BMRB: 17767
• Descriptor: Fatty acid-binding protein, liver, GLYCOCHOLIC ACID, GLYCOCHENODEOXYCHOLIC ACID (3 entities in total)
• Functional Keywords: heterotypic complex, bile acid binding protein, liver, bile acids, lipid binding protein, disulphide bridge
• Biological source: Gallus gallus (bantam,chickens)
• Cellular location: Cytoplasm: P80226
• Total number of polymer chains: 1
• Total formula weight: 15017.46

Authors

Tomaselli, S.,Cogliati, C.,Pagano, K.,Zetta, L.,Zanzoni, S.,Assfalg, M.,Molinari, H.,Ragona, L. (deposition date: 2011-07-07, release date: 2012-07-11, Last modification date: 2023-06-14)

• Primary citation: Tomaselli, S.,Assfalg, M.,Pagano, K.,Cogliati, C.,Zanzoni, S.,Molinari, H.,Ragona, L.; A disulfide bridge allows for site-selective binding in liver bile acid binding protein thereby stabilising the orientation of key amino acid side chains.; Chemistry, 18:2857-2866, 2012; PubMed: 22298334; DOI: 10.1002/chem.201102203

Experimental method

SOLUTION NMR