2LBI
N2-dG:N2-dG interstrand cross-link induced by trans-4-hydroxynonenal
Summary for 2LBI
Entry DOI | 10.2210/pdb2lbi/pdb |
NMR Information | BMRB: 17562 |
Descriptor | DNA (5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3'), (4S)-nonane-1,4-diol (3 entities in total) |
Functional Keywords | trans-4-hydroxynonenal, interstrand cross-link, dna |
Total number of polymer chains | 2 |
Total formula weight | 7487.04 |
Authors | Huang, H.,Kozekov, I.D.,Wang, H.,Kozekova, A.,Rizzo, C.J.,Stone, M.P. (deposition date: 2011-03-31, release date: 2012-04-04, Last modification date: 2024-05-15) |
Primary citation | Huang, H.,Wang, H.,Kozekova, A.,Rizzo, C.J.,Stone, M.P. Formation of a N2-dG:N2-dG carbinolamine DNA cross-link by the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N2-dG adduct. J.Am.Chem.Soc., 133:16101-16110, 2011 Cited by PubMed: 21916419DOI: 10.1021/ja205145q PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report