2L6E

NMR Structure of the monomeric mutant C-terminal domain of HIV-1 Capsid in complex with stapled peptide Inhibitor

Replaces:  2K1C

Summary for 2L6E

• Entry DOI: 10.2210/pdb2l6e/pdb
• NMR Information: BMRB: 17307
• Related PRD ID: PRD_000966
• Descriptor: Capsid protein p24, NYAD-13 stapled peptide inhibitor (2 entities in total)
• Functional Keywords: protein-stapled peptide complex, viral protein - peptide inhibitor complex, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Human immunodeficiency virus 1
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P35963
• Total number of polymer chains: 2
• Total formula weight: 13234.22

Authors

Bhattacharya, S.,Zhang, H.,Debnath, A.K.,Cowburn, D. (deposition date: 2010-11-18, release date: 2010-12-29, Last modification date: 2023-11-15)

• Primary citation: Bhattacharya, S.,Zhang, H.,Debnath, A.K.,Cowburn, D.; Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid.; J.Biol.Chem., 283:16274-16278, 2008; PubMed: 18417468; DOI: 10.1074/jbc.C800048200

Experimental method

SOLUTION NMR