2L6E

NMR Structure of the monomeric mutant C-terminal domain of HIV-1 Capsid in complex with stapled peptide Inhibitor

Replaces:  2K1C

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Capsid protein p24	polymer	105	11488.1	1	UniProt (P35963) Pfam (PF19317)	Human immunodeficiency virus 1
2	B (B)	NYAD-13 stapled peptide inhibitor	polymer	14	1746.2	1	BIRD (PRD_000966)

Sequence modifications

A: 148 - 231 (UniProt: P35963)

PDB	External Database	Details
Met 127	-	initiating methionine
Gly 128	-	expression tag
Ser 129	-	expression tag
Ser 130	-	expression tag
His 131	-	expression tag
His 132	-	expression tag
His 133	-	expression tag
His 134	-	expression tag
His 135	-	expression tag
His 136	-	expression tag
Ser 137	-	expression tag
Ser 138	-	expression tag
Gly 139	-	expression tag
Leu 140	-	expression tag
Val 141	-	expression tag
Pro 142	-	expression tag
Arg 143	-	expression tag
Gly 144	-	expression tag
Ser 145	-	expression tag
His 146	-	expression tag
Met 147	-	expression tag
Ala 184	Trp 316	engineered mutation
Ala 185	Met 317	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	13234.2
All*	Total formula weight	13234.2

*Water molecules are not included.