2L5K

Solution structure of truncated 23-mer DNA MUC1 aptamer

Summary for 2L5K

• Entry DOI: 10.2210/pdb2l5k/pdb
• Descriptor: DNA (5'-R(*(N68)P*G)-D(*CP*AP*GP*TP*TP*GP*AP*TP*CP*CP*TP*TP*TP*GP*GP*AP*TP*AP*CP*CP*CP*TP*GP*GP*T)-3') (1 entity in total)
• Functional Keywords: nmr solution structure, dyana and bce models, ttt triloop containing dna, truncated dna muc1 aptamer sequence, binding nucleotides, dna
• Total number of polymer chains: 1
• Total formula weight: 8164.29

Authors

Cognet, J.,Baouendi, M.,Hantz, E.,Missailidis, S.,Herve du Penhoat, C.,Piotto, M. (deposition date: 2010-11-02, release date: 2011-12-07, Last modification date: 2024-05-01)

• Primary citation: Baouendi, M.,Cognet, J.A.,Ferreira, C.S.,Missailidis, S.,Coutant, J.,Piotto, M.,Hantz, E.,Herve du Penhoat, C.; Solution structure of a truncated anti-MUC1 DNA aptamer determined by mesoscale modeling and NMR.; Febs J., 279:479-490, 2012; PubMed: 22129448; DOI: 10.1111/j.1742-4658.2011.08440.x

Experimental method

SOLUTION NMR