2L46

C-terminal zinc finger of the HIVNCp7 with platinated DNA

Summary for 2L46

Related2L44 2L45
DescriptorC-TERMINAL ZINC KNUCLE OF THE HIV-NCP7, DNA (5'-D(P*TP*AP*CP*GP*CP*C)-3'), ZINC ION (3 entities in total)
Functional Keywordsncp7, hiv, platinum, viral protein-dna complex, viral protein/dna
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
Total number of polymer chains2
Total molecular weight4065.21
Authors
Quintal, S.,Viegas, A.,Cabrita, E.,Farrell, N.,Erhardt, S. (deposition date: 2010-10-01, release date: 2011-12-14, Last modification date: 2012-06-20)
Primary citation
Quintal, S.,Viegas, A.,Erhardt, S.,Cabrita, E.J.,Farrell, N.P.
Platinated DNA affects zinc finger conformation. Interaction of a platinated single-stranded oligonucleotide and the C-terminal zinc finger of nucleocapsid protein HIVNCp7.
Biochemistry, 51:1752-1761, 2012
PubMed: 22303928 (PDB entries with the same primary citation)
DOI: 10.1021/bi201834g
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers20.3%17.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2l46
no rotation
Molmil generated image of 2l46
rotated about x axis by 90°
Molmil generated image of 2l46
rotated about y axis by 90°