2KXH

Solution structure of the first two RRM domains of FIR in the complex with FBP Nbox peptide

Summary for 2KXH

• Entry DOI: 10.2210/pdb2kxh/pdb
• Related: 2KXF
• Descriptor: Poly(U)-binding-splicing factor PUF60, peptide of Far upstream element-binding protein 1 (2 entities in total)
• Functional Keywords: rrm, fir, fbp, protein-protein complex, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 25084.54

Authors

Cukier, C.D.,Ramos, A.,Hollingworth, D.,Diaz-Moreno, I.,Kelly, G. (deposition date: 2010-05-05, release date: 2010-08-18, Last modification date: 2019-12-18)

• Primary citation: Cukier, C.D.,Hollingworth, D.,Martin, S.R.,Kelly, G.,Diaz-Moreno, I.,Ramos, A.; Molecular basis of FIR-mediated c-myc transcriptional control.; Nat.Struct.Mol.Biol., 17:1058-1064, 2010; PubMed: 20711187; DOI: 10.1038/nsmb.1883

Experimental method

SOLUTION NMR