2KXH

Solution structure of the first two RRM domains of FIR in the complex with FBP Nbox peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Poly(U)-binding-splicing factor PUF60	polymer	199	21927.0	1	UniProt (Q9UHX1) Pfam (PF00076) In PDB	Homo sapiens (human)	60 kDa poly(U)-binding-splicing factor, FUSE-binding protein-interacting repressor, FBP-interacting repressor, Siah-binding protein 1, Siah-BP1, Ro-binding protein 1, RoBP1
2	B	peptide of Far upstream element-binding protein 1	polymer	31	3157.5	1	UniProt (Q96AE4) In PDB	Homo sapiens (human)	FUSE-binding protein 1, FBP, DNA helicase V, hDH V

Sequence modifications

A: 102 - 297 (UniProt: Q9UHX1)

PDB	External Database	Details
Gly 99	-	expression tag
Ala 100	-	expression tag
Met 101	-	expression tag

B: 27 - 52 (UniProt: Q96AE4)

PDB	External Database	Details
Gly 22	-	expression tag
Ala 23	-	expression tag
Met 24	-	expression tag
Gly 25	-	expression tag
Tyr 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25084.5
All*	Total formula weight	25084.5

*Water molecules are not included.