2KTM
Solution NMR structure of H2H3 domain of ovine prion protein (residues 167-234)
Summary for 2KTM
| Entry DOI | 10.2210/pdb2ktm/pdb |
| Related | 1tpx 1tqb 1xyu 1y2s |
| Descriptor | Major prion protein (1 entity in total) |
| Functional Keywords | h2h3, prion protein, peptide folding, fibrilization core, cell membrane, membrane, prion, membrane protein |
| Biological source | Ovis aries (domestic sheep,lambs,wild sheep) |
| Total number of polymer chains | 1 |
| Total formula weight | 10244.29 |
| Authors | Pastore, A.,Adrover, M.,Pauwels, K.,de Chiara, C.,Prigent, S.,Rezeai, H. (deposition date: 2010-02-04, release date: 2010-04-07, Last modification date: 2021-11-10) |
| Primary citation | Adrover, M.,Pauwels, K.,Prigent, S.,de Chiara, C.,Xu, Z.,Chapuis, C.,Pastore, A.,Rezaei, H. Prion fibrillization is mediated by a native structural element that comprises helices H2 and H3. J.Biol.Chem., 285:21004-21012, 2010 Cited by PubMed: 20375014DOI: 10.1074/jbc.M110.111815 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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