2KRX

Solution NMR Structure of asl3597 from Nostoc sp. PCC7120. Northeast Structural Genomics Consortium Target ID Nsr244.

Summary for 2KRX

• Entry DOI: 10.2210/pdb2krx/pdb
• NMR Information: BMRB: 16652
• Descriptor: Asl3597 protein (1 entity in total)
• Functional Keywords: structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, unknown function
• Biological source: Nostoc sp.
• Total number of polymer chains: 1
• Total formula weight: 10988.45

Authors

Feldmann, E.A.,Ramelot, T.A.,Yang, Y.,Lee, D.K.,Ciccosanti, C.,Janjua, H.A.,Liu, J.,Rost, B.,Acton, T.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Kennedy, M.A.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2009-12-22, release date: 2010-03-16, Last modification date: 2024-05-22)

Primary citation

Feldmann, E.A.,Ramelot, T.A.,Yang, Y.,Xiao, R.,Acton, T.B.,Everett, J.K.,Montelione, G.T.,Kennedy, M.A.
Solution NMR structure of Asl3597 from Nostoc sp. PCC7120, the first structure from protein domain family PF12095, reveals a novel fold.
Proteins, 80:671-675, 2012

PubMed Abstract: The protein domain family PF12095 (DUF3571) is a functionally uncharacterized family of small proteins conserved from cyanobacteria to plants that are typically 85 to 95 amino acids in length in cyanobacteria. In this report, we describe the solution NMR structure of the 86-residue protein Asl3597 from Nostoc sp. PCC7120. The structure of Asl3597, which constitutes the first three-dimensional structure from protein family PF12095, has a unique α/β sandwich fold consisting of four anti-parallel β-strands opposite three continuous α-helices. Asl3597 may have a role in the assembly of the hydrophilic subcomplex of the cyanobacterial NAD(P)H complex as suggested by data for the orthologous Chlororespiratory reduction 7 protein from Arabidopsis thaliana.

PubMed: 22113821
DOI: 10.1002/prot.23236

Experimental method

SOLUTION NMR