2KNH

The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide

Summary for 2KNH

• Entry DOI: 10.2210/pdb2knh/pdb
• NMR Information: BMRB: 16467
• Descriptor: Protein CBFA2T1, Transcription factor 12 (2 entities in total)
• Functional Keywords: aml1-eto, etafh, heb, dna-binding, metal-binding, nucleus, proto-oncogene, transcription, transcription regulation, zinc-finger, developmental protein, phosphoprotein, transcription regulator
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 13613.66

Authors

Park, S.,Cierpicki, T.,Tonelli, M.,Bushweller, J.H. (deposition date: 2009-08-25, release date: 2009-10-06, Last modification date: 2020-02-26)

• Primary citation: Park, S.,Chen, W.,Cierpicki, T.,Tonelli, M.,Cai, X.,Speck, N.A.,Bushweller, J.H.; Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.; Blood, 113:3558-3567, 2009; PubMed: 19204326; DOI: 10.1182/blood-2008-06-161307

Experimental method

SOLUTION NMR